Other Nanopipetting in laboratory automation

Small scale dilution is a major requirement of the pharmaceutical laboratory. Nanolitre transfers from mother-plate to daughter-plate eliminate the need for serial dilutions and improve accuracy and precision while saving time and money by eliminating consumables and washes. These transfers can be in the low nanolitre/nanoliter volume region.

categories Genomic Solutions Innovadyne Labcyte Thermo TTP

The EDC ATS-100 pipettes volumes down to 1 nanolitre using a state-of-the-art acoustic powered drop transfer system.

The EDC ATS-100 is an affordable non-contact, acoustic, nanolitre liquid dispenser which uses low energy acoustics so no damage occurs to transferred materials or source plates. Safe for all biological fluids (including cells).

The ATS-100 creates non-contact quantitative microarrays, even on top of existing arrays, without the need for tips. Suitable for use with proteins, tissues and whole blood.

• plate reformatting
• compound library screening
• assay development
• cherry picking
• serial dilutions (IC50s)
• sample transfer in and out of 384, 1536 and 3456 well plates

• Precise and controlled transfer of chemical and biological compounds
• Dispense wide range of fluids e.g. 100% DMSO, aqueous buffers, glycerol solutions.
• User tunable for new liquids
• Dispense volumes between 1.0 - 1,000nl per location
• Low dead volumes. e.g.<1.0μl for 1536 well plate
• Can be easily integrated to produce a complete high throughput screening system
• Protocols are remotely configured and downloaded to the ATS-100 for processing
• Software handles multiple source plates, only one file required for cherry picking
• User-tunable unit drop volumes to optimize resolution or throughput
• Continuously drain wells from top to bottom, independent of neighbouring liquid levels
• real-time measurement of all liquid levels in all wells performed.

paa have automated this device with a number of robot platforms, including a demonstration system at PTC in New Jersey (USA).